• Emi protein consists of an

  2021-01-28

  

  Emi2 protein consists of an N-terminal regulatory region and a C-terminal functional region. The C-terminal region contains a destruction box (D-box), which likely competes with APC/C substrates (including cyclin B) for APC/C binding, and a zinc-binding region (ZBR), which somehow inhibits APC/C ubi

• Fusion genes are formed as the result of either structural

  2021-01-28

  

  Fusion genes are formed as the result of either structural chromosomal rearrangement including, primarily, translocation, inversion, amplification and deletion, or non-structural aberrations caused by cis- and trans-splicing or transcriptional read-through. Such events are known to play important ro

• Baicalein trihydroxyflavone was first isolated from the

  2021-01-28

  

  Baicalein (5,6,7- trihydroxyflavone) was first isolated from the roots of Scutellaria baicalensis Georgi (Lamiaceae family), a medicinal plant with diverse therapeutic implications; antibacterial, antiviral, and anti-inflammatory properties. It has been found that baicalein benefits neuroinflammatio

• As a support chitosan presents interesting characteristics t

  2021-01-28

  

  As a support, chitosan presents interesting characteristics that reinforce its great potential for enzyme immobilization [18,19]. Firstly, it is produced from renewable natural sources in addition to being biodegradable and water insoluble [20,21]. Also, the main peculiarity in the chitosan structur

• Developmental relationships between CD bright and CD dim NK

  2021-01-28

  

  Developmental relationships between CD56bright and CD56dim NK Costunolide remain unresolved; however, several studies indicate that the former is a precursor of the latter. An NK subset with intermediate features between CD56bright and CD56dim has been identified, corroborating this developmental tr

• br Author Contributions br Acknowledgments br

  2021-01-28

  

  Author Contributions Acknowledgments Introduction Osteoporosis is a common bone disease that frequently leads to disruption of the alveolar and systemic bones with age. Novel osteoanabolic strategies to treat osteoporotic bone loss or augment fracture repair efficiently are desired. Since b

• br Transparency document br Main Text The centrosome is

  2021-01-28

  

  Transparency document Main Text The centrosome is a non-membrane-bound organelle found in most animal cells. It has several important functions, including control of cilia formation, microtubule organization and nucleation, spindle assembly and transport of organelles and vesicles. Centrosomes

• br Materials and methods br Statistical analysis All statist

  2021-01-28

  

  Materials and methods Statistical analysis All statistical analyses were performed using SPSS software version 20. Protein CRT0044876 data of DNMTs and clinicopathological parameters were collected. Mann-Whitney U Test was used to assess the differential expression of nonparametric data of DNM

• Since anti MMP Therapy anti iNOS therapy TNF

  2021-01-28

  

  Since, anti-MMP Therapy [9], anti-iNOS therapy [10], TNF-α and IL-1β inhibitor (Diacerhein) [11] etc. are some of the disease modifying anti-osteoarthritis drugs have been used. But their action based on the evidence from the clinical trial and scientific literature suggesting the therapeutic effica

• Autophagy alterations are frequently reported

  2021-01-28

  

  Autophagy alterations are frequently reported as one of the pathological mechanisms contributing to neurodegenerative diseases, due to incomplete removal of protein MPI-0479605 in the brain [30,41]. It was over a decade ago when mutations in PARK8 encoding for the LRRK2 protein were described as a m

• br Materials and methods br Results br Discussion CHIKV is

  2021-01-28

  

  Materials and methods Results Discussion CHIKV is an important arthropod borne virus with substantial impact on global health and cause a major viral disease that requires the development of antiviral drug to combat chikungunya disease. Virus specific proteases have particularly become an a

• Unlike many forms of SNHL

  2021-01-27

  

  Unlike many forms of SNHL, cCMV may be treatable. The antiviral drug valganciclovir (VGCV) has been proposed to improve hearing, speech, and language outcomes associated with this infection [6]. A recent publication from the CASG (Collaborative Antiviral Study Group) reported that a six-month course

• Imipenem br Acknowledgments br Introduction Cell cycle arres

  2021-01-27

  

  Acknowledgments Introduction Cell cycle arrest or delay may occur at 3 major checkpoints, i.e. G1/S, intra-S and G2/M. p53 has a central role in controlling the G1/S checkpoint, and its loss or deactivation, occurring in the majority of cancers, forces cancer cells to rely on the S and G2/M ch

• BMX-IN-1 br Introduction Cell transplantation therapies

  2021-01-27

  

  Introduction Cell transplantation therapies using embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC)-derived retinal tissue (ESC/iPSC retina) or BMX-IN-1 have emerged as therapeutic options for retinal degeneration following recent breakthroughs. A number of groups have shown tha

• Accordingly we prepared three compounds and as shown in

  2021-01-27

  

  Accordingly, we prepared three compounds (, , and ) as shown in . Condensation of commercially available Mesoridazine receptor with glycine methyl ester gave amide . A Friedel–Crafts reaction between compound and 4-methyl valeryl chloride in the presence of aluminum chloride mainly produced unde

14918 records 735/995 page Previous Next First page 上5页 731732733734735 下5页 Last page